The preparation and pharmacological properties of ψ-corbasil
- 1 December 1969
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 21 (Supplement) , 199S-205S
- https://doi.org/10.1111/j.2042-7158.1969.tb08375.x
Abstract
The synthesis is described of threo-α-methyl noradrenaline (ψ-corbasil). The assignments of the erythro and threo configurations to corbasil and ψ-corbasil respectively are supported by the evidence of the nmr spectra. Some preliminary results are reported for the relative pharmacological activity of the two isomers at α- and β-adrenergic receptors.Keywords
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