Long‐term effects of the menopause and sex hormones on skin thickness

Publisher Website
Google Scholar
Abstract
Skin collagen content and skin thickness in a group of postmenopausal women who were treated with sex hormone implants were compared with those in an untreated group of similar women. Both skin collagen content and thickness were found to be significantly greater in the treated than in the untreated group. In the untreated women skin collagen content declined in relation to menopausal age but not to chronological age. No correlation was found with menopausal age, chronological age or duration of therapy in the treated group. Evidently, skin collagen is influenced by the sex hormone status and declines after the menopause, contributing to the increase in urinary hydroxyproline excretion that was reported to occur at this time.