Treatment of pulmonary aspergillosis with di-iodohydroxyquinoline.

Abstract
Patients (13) with a clinical diagnosis of pulmonary aspergillosis were treated with the anti-amoebic drug di-iodohydroxyquinoline, 1500-1800 mg/day orally for 20 days. All were precipitin positive before treatment and all but 1 became negative after treatment. Sputum became negative in all 10 patients in whom it had been positive before treatment. Clinical improvement was marked in 4 patients, moderate in 3 and slight in 3, no change occurring in the remaining 3. Di-iodohydroxyquinoline may be of value in the treatment of pulmonary aspergillosis.