A new protocol for the syntheses of (E)-3-benzylidenechroman-4-ones: a simple synthesis of the methyl ether of bonducellin
- 1 January 1998
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 16,p. 1639-1640
- https://doi.org/10.1039/a804796k
Abstract
Development of a simple new methodology for the synthesis of (E)-3-benzylidenechroman-4-ones using methyl 3-aryl-3-hydroxy-2-methylenepropanoates, the Baylis–Hillman adducts derived from methyl acrylate, and the application of this methodology for the synthesis of the methyl ether of bonducellin, an important natural product, and 3-(4-methoxybenzylidene)-6-methoxychroman-4-one, an antifungal agent, are described.Keywords
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