Induction of vascular endothelial growth factor expression in synovial fibroblasts by prostaglandin E and interleukin‐1: a potential mechanism for inflammatory angiogenesis

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Abstract
Inflammatory mediators such as prostaglandin E2 (PGE2) and interleukin‐1 (IL‐1) induce angiogenesis by yet undefined mechanisms. We demonstrate that PGE2 and IL‐1 induces the expression of vascular e...