Synthesis and biological evaluation of novel indoloazepine derivatives as non-peptide vasopressin V2 receptor antagonists
- 1 February 2003
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 13 (4) , 753-756
- https://doi.org/10.1016/s0960-894x(02)01059-4
Abstract
No abstract availableKeywords
This publication has 16 references indexed in Scilit:
- An Efficient Synthesis of Optical Isomers of Vasopressin V2 Receptor Antagonist OPC-41061 by Lipase-catalyzed Enantioselective TransesterificationHETEROCYCLES, 2001
- 7-Chloro-5-hydroxy-1-[2-methyl-4-(2-methylbenzoylamino)benzoyl]-2,3,4,5-tetrahydro-1H-1-benzazepine (OPC-41061): A potent, orally active nonpeptide arginine vasopressin V2 receptor antagonistBioorganic & Medicinal Chemistry, 1999
- 5-Fluoro-2-methyl-N-[4-(5H-pyrrolo[2,1-c]- [1,4]benzodiazepin-10(11H)-ylcarbonyl)-3- chlorophenyl]benzamide (VPA-985): An Orally Active Arginine Vasopressin Antagonist with Selectivity for V2ReceptorsJournal of Medicinal Chemistry, 1998
- Orally Active, Nonpeptide Vasopressin V2 Receptor Antagonists: A Novel Series of 1-[4-(Benzoylamino)benzoyl]-2,3,4,5-tetrahydro-1H-benzazepines and Related CompoundsJournal of Medicinal Chemistry, 1996
- Protein kinase C modulators. Indolactams. 2.1 Alkylation of 4-nitroindole by Grignard reagents. Synthesis of (-)-7-octylindolactam VTetrahedron Letters, 1994
- Orally active, nonpeptide vasopressin V1 antagonists. A novel series of 1-(1-substituted 4-piperidyl)-3,4-dihydro-2(1H)-quinolinonesJournal of Medicinal Chemistry, 1993
- 4-NITROINDOLEOrganic Syntheses, 1987
- Indoles. V. Syntheses and reactions of cycloalkanon[c,d]indole derivatives.CHEMICAL & PHARMACEUTICAL BULLETIN, 1977
- Azepinoindoles. III. 3,4,5,6-Tetrahydro-1H-azepino[4,3,2,-cd]indolesThe Journal of Organic Chemistry, 1967
- A Synthesis of 1,3,4,5-Tetrahydropyrrolo[4,3,2-de]quinolineThe Journal of Organic Chemistry, 1964