Life-Threatening Hyperkalemia: A Complication of Spironolactone for Heart Failure in a Patient with Renal Insufficiency
- 1 July 2002
- journal article
- case report
- Published by Wolters Kluwer Health in Anesthesia & Analgesia
- Vol. 95 (1) , 39-41
- https://doi.org/10.1097/00000539-200207000-00006
Abstract
Serum potassium concentration should be measured immediately before operation to detect hyperkalemia in heart failure patients treated with spironolactone. Renal insufficiency, advanced age, potassium supplementation, decompensated congestive heart failure, and a spironolactone dose larger than 25 mg/d increase the risk of hyperkalemia as a consequence of spironolactone therapy.Keywords
This publication has 4 references indexed in Scilit:
- Life-threatening hyperkalemia during combined therapy with angiotensin-converting enzyme inhibitors and spironolactone: an analysis of 25 casesThe American Journal of Medicine, 2001
- Serious adverse events experienced by patients with chronic heart failure taking spironolactoneHeart, 2001
- The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart FailureNew England Journal of Medicine, 1999
- Adverse Reactions to SpironolactoneJAMA, 1973