Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation
Top Cited Papers
Open Access
- 1 September 2003
- journal article
- review article
- Published by Hindawi Limited in Cellular Microbiology
- Vol. 5 (9) , 581-592
- https://doi.org/10.1046/j.1462-5822.2003.00304.x
Abstract
The innate immune system is the most ancestral and ubiquitous system of defence against microbial infection. The microbial sensing proteins involved in innate immunity recognize conserved and often s...Keywords
This publication has 71 references indexed in Scilit:
- An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acidNature Immunology, 2003
- Card15 gene overexpression in mononuclear and epithelial cells of the inflamed Crohn's disease colonGut, 2003
- Targeted Disruption of Pyrin, the FMF Protein, Causes Heightened Sensitivity to Endotoxin and a Defect in Macrophage ApoptosisPublished by Elsevier ,2003
- Gene–environment interaction modulated by allelic heterogeneity in inflammatory diseasesProceedings of the National Academy of Sciences, 2003
- Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophilaNature Genetics, 2002
- De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal‐onset multisystem inflammatory disease (NOMID): A new member of the expanding family of pyrin‐associated autoinflammatory diseasesArthritis & Rheumatism, 2002
- Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosisArthritis & Rheumatism, 2002
- The mitochondrial apoptosome: a killer unleashed by the cytochrome seasTrends in Biochemical Sciences, 2001
- The PYRIN domain: a novel motif found in apoptosis and inflammation proteinsCell Death & Differentiation, 2000
- Human CARD4 Protein Is a Novel CED-4/Apaf-1 Cell Death Family Member That Activates NF-κBJournal of Biological Chemistry, 1999