THE EFFECT OF CASTRATION ON THE INCORPORATION OF ACETATE-1-C14 INTO CHOLESTEROL IN THE ALBINO RAT

Abstract
In male castrated albino rats the incorporation of C14 from acetate-1-C14 into the cholesterol of the liver, the adrenals, and the heart is significantly increased as compared to the incorporation found in the same tissues of control animals. The metabolic C14O2 originating from the injected acetate is not affected by castration, nor is the total activity of the urine. There is, incidentally, a significant increase in adrenal weight following castration.