Identification of 5-Hydroxytryptophol as a Serotonin Metabolite In Man.
- 1 July 1966
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 122 (3) , 890-893
- https://doi.org/10.3181/00379727-122-31281
Abstract
Summary 5-Hydroxytryptophol has been isolated, identified, and measured in urine of subjects with carcinoid tumors. In the urine of normal subjects and of patients with carcinoid tumors who ingested 5-HT-C14, 2.3% of the excreted C14 was attributable to 5-HTOH and its conjugates and 82.3% to 5-HIAA. These data show that 5-HTOH is a 5-HT metabolite in man as well as in animals.This publication has 3 references indexed in Scilit:
- FREE AND CONJUGATED SEROTONIN EXCRETION IN CARCINOID SYNDROME1965
- 5-Hydroxytryptophol: a metabolite of 5-hydroxytryptamine in ratsBiochemical Journal, 1962
- THE IDENTIFICATION OF 5-HYDROXY-3-INDOLEACETIC ACID IN NORMAL URINE AND A METHOD FOR ITS ASSAYJournal of Biological Chemistry, 1955