Effects of Five Alpha-Blockers on the Hypogastric Nerve Stimulation of the Canine Lower Urinary Tract
- 1 July 1988
- journal article
- research article
- Published by Wolters Kluwer Health in Journal of Urology
- Vol. 140 (1) , 165-167
- https://doi.org/10.1016/s0022-5347(17)41519-9
Abstract
Electrical stimulation of the hypogastric nerve increased both urethral and bladder pressures of anaesthetized male dogs, without affecting cardiovascular parameters. Intravenous injections of prazosin, phentolamine, thymoxamine, phenoxybenzamine and yohimbine inhibited the urethral pressure increase in a dose-dependent manner, but the increase in bladder pressure was not modified by these alpha-blockers.This publication has 16 references indexed in Scilit:
- Role of sympathetic blocking agents in outflow obstructionClinical Science, 1986
- α1- and α2-adrenoceptors in the smooth muscle of mal and female rabbit urethraEuropean Journal of Pharmacology, 1986
- Experimental Evidence for a Central Nervous system Site of Action in the Effect of Alpha-Adrenergic Blockers on the External Urinary SphincterJournal of Urology, 1984
- Pharmacological analysis of the responses of the feline urethra to autonomic nerve stimulationJournal of the Autonomic Nervous System, 1983
- THE ROLE OF THE HYPOGASTRIC NERVE IN BLADDER AND URETHRAL ACTIVITY OF THE DOGBritish Journal of Pharmacology, 1979
- Adrenoceptor and Cholinoceptor Mediated Responses of the Isolated Human UrethraScandinavian Journal of Urology and Nephrology, 1977
- Disorders of micturition Neuropharmacologic basis and results of drug therapyUrology, 1976
- The Vascular Component in the Production of Intraurethral PressureJournal of Urology, 1972
- Effect upon the urinary bladder of unilateral stimulation of hypogastric nerves in the dogThe Anatomical Record, 1958
- The innervation of the bladder and urethra1The Journal of Physiology, 1907