A Convenient Synthetic Approach to New α-(9-Fluorenylmethoxycarbonylamino) alkylphosphonic Acid Derivatives
- 1 January 1992
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1992 (12) , 1226-1228
- https://doi.org/10.1055/s-1992-26344
Abstract
Benzyl hydrogen α-(9-fluorenylmethoxycarbonylamino)alkylphosphonates 4, obtained by the sodium metaperiodate oxidation of the corresponding phosphinates 3, were converted to the chloridates 5 and coupled with the N ε-protected lysine benzyl ester to afford peptides 6 containing a phosphonamide bond.Keywords
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