Ultrastructure of Calymmatobacterium granulomatis in Lesions of Granuloma Inguinale

Publisher Website
Google Scholar
Abstract
Biopsy specimens from the lesions of 14 patients with granuloma inguinale were examined by EM. C. granulomatis, the presumed causative agent, was observed within the phagosomes of many macrophages, but only rarely in polymorphonuclear leukocytes. The morphology of the organism was that of a gram-negative bacterium having a large capsule and no flagella. These morphologic observations are consistent with published findings suggesting that this organism is related antigenically to organisms of the genus Klebsiella.