MELORHEOSTOSIS LÉRI: A FLOWING HYPEROSTOSIS OF A SINGLE EXTREMITY
- 27 February 1932
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 98 (9) , 705-709
- https://doi.org/10.1001/jama.1932.02730350019005
Abstract
In 1922, Léri and Joanny1described a new type of hyperplastic bone lesion which is confined to a single extremity, extending from one end to the other in a linear track but usually leaving a few unaffected areas along the course. The term "melorheostosis" is derived from the Greek (μ[unk]λος, limb; ρ[unk]ω, flow) and means "flowing hyperostosis of a limb." The disease was independently described three years later by Lewin and McLeod,2as an osteosclerosis. Other terms applied by early writers on the subject were "osteosis eburnisans monomelica"3and "osteopathia hyperostotica congenita (unius membri)."4 PATHOLOGY The disease is characterized by proliferation of ivorylike new bone in the cortical areas. The lesions may assume different forms in different parts of the extremity, sometimes resembling osteoma, at other times suggestive of spurs, periostosis, calcinosis, or osteoplastic malignant conditions. When the proliferative process has caused considerable expansion, the hyperplasticKeywords
This publication has 0 references indexed in Scilit: