A method for localized and longlasting microapplication of drugs into nervous tissue of freely moving animals
- 1 July 1979
- journal article
- research article
- Published by Springer Nature in Experimental Brain Research
- Vol. 36 (2) , 259-264
- https://doi.org/10.1007/bf00238909
Abstract
A method is described for localized microapplication of drugs into nervous tissue of freely moving rats. Fairly constant release of material was observed over a period of more than three weeks. The amount of substance released was small because the rate of release was determined largely by diffusion rather than by mass movement of solution.Keywords
This publication has 9 references indexed in Scilit:
- Induction and maintenance of free postsynaptic membrane thickenings in the adult superior cervical ganglionJournal of Neurocytology, 1979
- Plasticity in dendrites shown by continuous GABA administration in superior cervical ganglion of adult ratNature, 1978
- Local perfusion of noradrenaline maintains visual cortical plasticityNature, 1978
- A pressure system for intracellular and extracellular ejections of picoliter volumesBrain Research, 1977
- A technique for the ejection of solutions from glass micropipettes, based on digitally controlled thermal expansion [proceedings].1977
- Microimplantation of [3H]proline on a single bead of ion-exchange resinBrain Research, 1977
- A pressure device for intracellular injectionCellular and Molecular Life Sciences, 1974
- An improved microinjection technique in Paramecium aureliaExperimental Cell Research, 1974
- A microelectrophoretic delivery technique for use with horseradish peroxidaseBrain Research, 1974