NERVE CONDUCTION VELOCITY AND EQUILIBRATION

Abstract
The velocity of propagation of the nerve impulse (and the shape of the action potential) in frog sciatic and dog phrenic nerves has been studied with the aid of the cathode ray oscillograph. During equilibration, produced by continued tetanization at frequencies up to 300 per sec., conduction rate and potential amplitude fall, at first rapidly, then more slowly, to an equilibrium level less than 2/3 normal reached in 1/4 hr. During a similar rest period, inverse changes restore the nerve essentially to its initial state. Small diameter fibers are more affected than large. These findings complement similar ones regarding heat production, threshold, etc., and are in agreement with theoretical expectations.

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