GLYCOSYLATED HEMOGLOBIN-A2 COMPONENTS

  • 1 January 1980
    • journal article
    • research article
    • Vol. 56  (3) , 571-572
Abstract
Partially purified [human] Hb A2 was examined for the existence of glycosylated components by isoelectric focusing and by acid agar gel electrophoresis. Bands analogous to the glycohemoglobin derivatives of Hb A, Hb-A1a.b.c, were readily detected. Evidence that these minor bands are in fact glycohemoglobins was obtained by showing that 14C-glucose bound to Hb A2 moved with these minor bands. The amounts of the glycohemoglobin derivatives of Hb A2 were increased in the blood of diabetic patients.