Evaluation of the renal scanning agent N-succinyldesferrioxamine B in dogs

Abstract
The mechanism of the excretion of 67Ga-N-succinyldesferrioxamine B (SDF) was investigated in five healthy dogs. Comparison of the SDF clearance rates for whole blood and plasma as well as SDF renograms with those of 131I-o-iodohippuric acid (OIH) and 111In-diethy-lenetriamine-pentaacetic acid (DTPA) revealed that SDF is cleared by glomerular filtration and not by an active tubular transport mechanism.

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