COLLAGENASE IN SYNOVIAL-FLUID
- 1 January 1978
- journal article
- research article
- Vol. 7 (1) , 49-54
Abstract
Free human collagenase activity was demonstrated in all 13 normal, 5 osteoarthrotic and 54 rheumatoid synovial fluids studied. Osteoarthrotic, normal and rheumatoid fluids showed a free collagenase content increasing in that order. The total activities after trypsin activation did not differ significantly. The concentrations of .alpha.1-at [.alpha.1-antitrypsin] and .alpha.2-M [.alpha.2-macroglobulin] in synovial fluids reflected those in sera. The complex interactions between serum inhibitors, and free or latent collagenase released from both synovial cells and leukocytes are discussed.This publication has 12 references indexed in Scilit:
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