Certain patterns of karyotype evolution in chronic myelogeneous leukaemia
- 1 January 1975
- journal article
- Published by Springer Nature in Human Genetics
- Vol. 30 (2) , 113-119
- https://doi.org/10.1007/bf00291943
Abstract
The study of chromosome banding pattern of leukaemic cells in 15 patients with CML revealed t(9;22) in all cases. Similar additional chromosome abnormalities were observed in the terminal stage of the disease in 5 of 9 patients with aneuploid cell lines. The most frequent abnormalities were i(17q) and trisomy 8. The regularities of karyotype evolution in the terminal stage of CML are discussed.Keywords
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