Successful Treatment of Acquired Factor VIII Antibody by Extracorporeal Immunoadsorption
- 1 January 1991
- journal article
- case report
- Published by S. Karger AG in Acta Haematologica
- Vol. 85 (2) , 107-110
- https://doi.org/10.1159/000204868
Abstract
We report the successful treatment of a 59-year-old woman with acquired factor VIII inhibitor. The patient who had an extensive leg hematoma with a resultant neurologic defect was treated with extracorporeal immunoadsorption (IA) using protein A-Sepharose, factor VIII concentrates, azathioprine, and methyl-prednisolone. Extracorporeal IA reduced the titers of the inhibitor so that factor VIII concentrates could raise the level of factor VIII coagulant activity and stop the bleeding.Keywords
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