Kinetics of regeneration of metronidazole from hemiesters of maleic acid, succinic acid and glutaric acid in aqueous buffer, human plasma and pig liver homogenate
- 1 January 1988
- journal article
- research article
- Published by Elsevier in International Journal of Pharmaceutics
- Vol. 41 (1-2) , 121-129
- https://doi.org/10.1016/0378-5173(88)90144-5
Abstract
No abstract availableKeywords
This publication has 41 references indexed in Scilit:
- Identification and characterization of hepatic carboxylesterases hydrolyzing hydrocortisone estersBiochemical Pharmacology, 1985
- Strategies in the Design of Solution-Stable, Water-Soluble Prodrugs Ill: Influence of the Pro-Moiety on the Bioconversion of 21-Esters of CorticosteroidsJournal of Pharmaceutical Sciences, 1985
- Carboxyl Group Catalysis of Acyl Transfer Reactions in Corticosteroid 17- and 21 -MonoestersJournal of Pharmaceutical Sciences, 1984
- Influence of route of administration on the pharmacokinetics of methylprednisoloneJournal of Pharmacokinetics and Biopharmaceutics, 1983
- Pharmacokinetics of intravenous chloramphenicol sodium succinate in adult patients with normal renal and hepatic functionJournal of Pharmacokinetics and Biopharmaceutics, 1982
- Initial Rate Studies of Hydrolysis and Acyl Migration in Methylprednisolone 21-Hemisuccinate and 17-HemisuccinateJournal of Pharmaceutical Sciences, 1981
- Rearrangement of chloramphenicol-3-monosuccinateJournal of Pharmaceutical Sciences, 1980
- Intramolecular displacement of alkoxide ions by the ionised carboxy-group: hydrolysis of alkyl hydrogen dialkylmaleatesJournal of the Chemical Society, Perkin Transactions 2, 1974
- The Effect of Geminal Substitution Ring Size and Rotamer Distribution on the Intramolecular Nucleophilic Catalysis of the Hydrolysis of Monophenyl Esters of Dibasic Acids and the Solvolysis of the Intermediate AnhydridesJournal of the American Chemical Society, 1960
- Acid Ionization Constants of Alcohols. II. Acidities of Some Substituted Methanols and Related Compounds1,2Journal of the American Chemical Society, 1960