MUSCLE HEMOGLOBIN CONCENTRATION DURING GROWTH AS INFLUENCED BY DIET FACTORS

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Abstract
Litter mates (dogs) were divided in 2 groups and after weaning were fed an adequate synthetic bread ration or a bread ration plus large amounts of cooked liver. No differences in muscle hemoglobin concentration in the two groups were noted after 10 weeks'' feeding. After 15 to 20 weeks on these diets the liver-fed pups showed uniformly a distinct increase in blood hemoglobin levels and muscle hemoglobin concentration above the bread controls. After 25 to 30 weeks these differences in favor of the liver feeding may be more distinct. Blood hemoglobin levels are labile and easily disturbed and the body capacity for producing large amounts of hemoglobin is fortunately very great. By contrast the muscle hemoglobin levels are stable and not easily disturbed. Whether the body can produce large amounts of muscle hemoglobin must be left an open question but the growth requirements of new muscle hemoglobin are not large. The maintenance factor required to replace wear and tear of muscle hemoglobin is unknown.

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