Androgen Inhibits the Increases in Hypothalamic Corticotropin-Releasing Hormone (CRH) and CRH-lmmunoreactivity following Gonadectomy
- 1 January 1994
- journal article
- regulation of-hypothalamic-neurons
- Published by S. Karger AG in Neuroendocrinology
- Vol. 59 (3) , 228-234
- https://doi.org/10.1159/000126663
Abstract
To characterize the effect of androgens on the hypothalamo-pituitary-adrenal (HPA) axis we examined the regulation of corticotropin-releasing hormone (CRH) following gonadectomy and hormone replacement. Three-month-old male Fischer 344 (F344) rats were gonadectomized (GDX) or sham GDX. Control animals remained intact. Animals were sacrificed 1, 4, 7, 10, or 21 days following surgery. GDX rats had significantly elevated (pKeywords
This publication has 0 references indexed in Scilit: