Studies on Detoxication by the Perfused Liver
- 1 January 1963
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine
- Vol. 7 (1) , 53-57
- https://doi.org/10.1080/09553006314550841
Abstract
Synthesis of hippuric acid was determined in the isolated perfused liver of normal and x-irradiated rats with and without addition of glycine. An increase in synthesis of hippuric acid without addition of glycine was found in x-irradiated liver, indicating an expansion of the free glycine pool. On the other hand, synthesis of hippuric acid in x-irradiated liver was found to be slightly decreased when large amounts of glycine were present in the perfusate.Keywords
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