Abstract
A method of subtracting blood background during proberenography is presented which does not require a prior injection of RIHSA [131I-human serum albumin] and which produces results .apprx. 11% higher than the RIHSA method. The new method treats the renogram up to 2 1/2 min as a combination of a fraction of the blood curve and a fraction of the integral of the blood curve. Analysis of the data, using either a computer or a programmed calculator, enables these 2 fractions to be calculated, hence producing the background subtraction factor and the uptake constant.

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