Enzymatic Synthesis of Enantiomerically Pure Chiral Synthons: Lipase-Catalyzed Resolution of (R/S, 4E)-2-Methyl-4-hexen-l-ol

Abstract
The synthetically useful chiral synthons R and S (4E)-2-methyl-4-hexen-1-ol (1a) can be prepared enantiomerically pure by an enantioselective transacetylation with vinyl acetate of racemic 1a in dichloromethane catalyzed by a lipase from Pseudomonas fluorescens (PFL).

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