Prediction of Adverse Outcomes in Children with Sickle Cell Disease
Top Cited Papers
- 13 January 2000
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 342 (2) , 83-89
- https://doi.org/10.1056/nejm200001133420203
Abstract
The ability to identify infants with sickle cell anemia who are likely to have severe complications later in life would permit accurate prognostication and tailoring of therapy to match disease-related risks and facilitate planning of clinical trials. We attempted to define the features of such babies by following the clinical course of 392 children with sickle cell disease from infancy to about the age of 10 years.Keywords
This publication has 30 references indexed in Scilit:
- Effect of Hydroxyurea on the Frequency of Painful Crises in Sickle Cell AnemiaNew England Journal of Medicine, 1995
- Laboratory profile of sickle cell disease: A cross-sectional analysisJournal of Clinical Epidemiology, 1992
- Stroke in a cohort of patients with homozygous sickle cell diseaseThe Journal of Pediatrics, 1992
- Sickle Cell Disease as a Cause of Osteonecrosis of the Femoral HeadNew England Journal of Medicine, 1991
- Pain in Sickle Cell DiseaseNew England Journal of Medicine, 1991
- Tissue Destruction by NeutrophilsNew England Journal of Medicine, 1989
- Levels of Fetal Hemoglobin Necessary for Treatment of Sickle Cell DiseaseNew England Journal of Medicine, 1988
- Sickle Cell Chronic Lung DiseaseMedicine, 1988
- Bacteremia in sickle hemoglobinopathiesThe Journal of Pediatrics, 1986
- Two different molecular organizations account for the single alpha-globin gene of the alpha-thalassemia-2 genotype.Journal of Clinical Investigation, 1980