β‐Endorphin: intranasal administration increases the serum prolactin level in monkey
- 1 November 1986
- journal article
- research article
- Published by Wiley in International Journal of Peptide and Protein Research
- Vol. 28 (5) , 546-548
- https://doi.org/10.1111/j.1399-3011.1986.tb03291.x
Abstract
Human .beta.-endorphin has been administered by nasal spray technique at a dose of 0.02 mg per kg in female bonnet monkeys [Macaca radiata]. A significant increase of serum prolactin levels was observed within 30 min and maintained up to 60 min. In the same dose, intravenous injections of the hormone caused a marginal increase of prolactin levels only after 60 min. It was concluded that administration of .beta.-endorphin by nasal spray is more effective than the intravenous injection.Keywords
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