Clinical radionuclide perfusion lymphangiography

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Abstract
In an initial pilot study 99mTc-labeled human serum albumin was perfused directly into bipedal lymphatic cannulae prior to a standard lymphangiogram to assess rapidly normal and abnormal lymph flow patterns in the lower extremity, pelvic and para-aortic lymph chains. A continuing study of these patients shows that the radionuclide perfusion study, when negative, may prove more accurate in some patients than the standard lymphangiogram in predicting the clinical course and/or the results of histopathological lymph node examination. The radionuclide technique seems to meet, in this preliminary evaluation, the requirements for a pre-lymphangiogram screening study, particularly for use in high-risk patients.

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