Absence of Y specific DNA sequences in two siblings with 46XX hermaphroditism.
- 1 August 1989
- journal article
- research article
- Published by BMJ in Archives of Disease in Childhood
- Vol. 64 (8) , 1185-1187
- https://doi.org/10.1136/adc.64.8.1185
Abstract
We report two siblings with 46XX hermaphroditism in whom we were unable to show the presence of Y specific DNA sequences using the DNA probes Y-190, GMGY-7, pHY2.1, pDP34, and 27a. We conclude that an autosomal or X chromosome gene mutation is the most likely mechanism of inheritance in this family with 46XX hermaphroditism.Keywords
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