Immune Complexes in Myelofibrosis: a Possible Guide to Management

Abstract
Using a fluorescent technique intracellular immune complexes were found in the peripheral leukocytes in all of 12 patients with myelofibrosis studied. Fluorescent cells varied from 12-81%; with no relation to the total white count or any obvious clinical finding. Three of the patients with severe refractory anemia benefited from immunosuppressive therapy.