Abstract
The widely distributed black or brown pigments in the larvae of Xenopus laevis, Rana pipiens and Rana temporaria were examined histochemically and found to behave like malanin. The development and distribution of pigment was studied in Xenopus up to the time of metamorphosis and a similar study was made for certain stages in Rana pipiens and Rana temporaria. The effect of 0.01% phenylthiourea on pigmentation was found to differ in different areas of the larvae, pigmentation being reduced in some areas, unaffected in others, and even increased in still others. The significance of these differing responses is discussed in relation to the development and disposition of pigment, histological evidence of excretion of melanin, and the problem of pigment turnover.

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