DIPSTICK SCREENING FOR URINARY-TRACT INFECTION
- 3 September 1988
- journal article
- research article
- Vol. 74 (5) , 224-228
Abstract
In screening for urinary tract infection the leucocyte esterase test will detect almost all samples with significant pyuria and bacteriuria, but is relatively nonspecific. The nitrite test is more specific but less sensitivre and about one-third of the urinary tract infections in a large group of children were missed. The combination of screening tests results in greater overall accuracy both in the diagnosis and exclusion of urinary tract infection. Almost all cases of urinary tract infection were detected when either the leucocyte esterase or the nitrite screening test or both were positive. If both tests are negative, urinary tract infection is virutally excluded and unless the child is syptomatic, further urinalysis is unnecessary. Laboratory urinalysis is, however, necessary if any one screening test for leucocyte esterase or nitrite (or protein or haemoglobin) is positive. Combined biochemical screening for urinary tract infection with dipstick test strips is reliable and allows early diagnosis and management. By avoiding unnecessary urinalysis it is cost-effective for the patient and will significantly reduce the laboratory workload.This publication has 9 references indexed in Scilit:
- Urinary nitrite in symptomatic and asymptomatic urinary infection.Archives of Disease in Childhood, 1987
- Leucocyte esterase-nitrite screening method for pyuria and bacteriuria.Journal of Clinical Pathology, 1985
- Leucocyte esterase determination as a secondary procedure for urine screening.Journal of Clinical Pathology, 1985
- Evaluation of leukocyte esterase activity as a rapid screening technique for bacteriuriaJournal of Clinical Microbiology, 1982
- Rapid detection of pyuria by leukocyte esterase activityJAMA, 1981
- Detection of Urinary Leukocytes by Chemstrip-LJournal of Urology, 1981
- Problems of Spectrum and Bias in Evaluating the Efficacy of Diagnostic TestsNew England Journal of Medicine, 1978
- Home-Testing for Recurrent Bacteriuria, Using Nitrite StripsArchives of Pediatrics & Adolescent Medicine, 1978
- Survival of urinary leucocytesJournal of Clinical Pathology, 1966