PNEUMOPERITONEUM AND ANTIBIOTIC THERAPY

11 June 1960

journal article
research article
Published by American Medical Association (AMA) in JAMA

Vol. 173 (6) , 668-671
https://doi.org/10.1001/jama.1960.73020240008010d

Abstract

Pyogenic lung abscess with cavity formation is seldom mentioned in the literature dealing with chest disorders. Whether lung abscess occurs so infrequently that it is thought unimportant or whether it is considered too benign, self-limited, and responsive to antibiotics to require scientific study is not known. In 1957 Wolcott and Murphy¹stated that the prognosis and management of lung abscess has changed dramatically in the past 15 years. They reported on 70 patients treated since 1941. In 19 patients treated between 1941 to 1944 with sulfonamide and routine bronchoscopy the mortality was 31.5%. From 1945 to 1951, 29 patients were treated with penicillin given both parenterally and in an aerosol form and supplemented with routine bronchoscopy; five persons, or 17%, died. The third group comprised 27 patients treated from 1951 to 1955. Bronchoscopy was now used only to secure cultural material and for sensitivity studies. The drug of choice

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