Dystrophin‐deficient mdx mice display a reduced life span and are susceptible to spontaneous rhabdomyosarcoma
Top Cited Papers
Open Access
- 9 March 2007
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 21 (9) , 2195-2204
- https://doi.org/10.1096/fj.06-7353com
Abstract
Duchenne muscular dystrophy (DMD) is the most common, lethal genetic disorder of children. A number of animal models of muscular dystrophy exist, but the most effective model for characterizing the s...Keywords
Funding Information
- National Institutes of Health (PO1 AG015434)
This publication has 70 references indexed in Scilit:
- Contraction-induced injury to single permeabilized muscle fibers from mdx, transgenic mdx, and control miceAmerican Journal of Physiology-Cell Physiology, 2000
- Muscular dystrophies and the dystrophin–glycoprotein complexCurrent Opinion in Neurology, 1997
- Membrane abnormalities and Ca homeostasis in muscles of the mdx mouse, an animal model of the Duchenne muscular dystrophy: a reviewActa Physiologica Scandinavica, 1996
- Three muscular dystrophies: Loss of cytoskeleton-extracellular matrix linkageCell, 1995
- A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actinThe Journal of cell biology, 1993
- Mechanical properties of normal andmdx mouse sarcolemma: Bearing on function of dystrophinJournal of Muscle Research and Cell Motility, 1991
- Characterization of Dystrophin in Muscle-Biopsy Specimens from Patients with Duchenne's or Becker's Muscular DystrophyNew England Journal of Medicine, 1988
- The complete sequence of dystrophin predicts a rod-shaped cytoskeletal proteinCell, 1988
- Dystrophin: The protein product of the duchenne muscular dystrophy locusCell, 1987
- On Granular and Fatty Degeneration of the Voluntary MusclesJournal of the Royal Society of Medicine, 1852