The Many Pitfalls in the Diagnosis of Myeloma

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Abstract
The step-by-step process of clinical problem-solving is the subject of this new Journal feature. Information about a real patient is presented to an expert clinician in stages (boldface type), to simulate the way such information emerges in everyday clinical practice. In this exercise, the discussant, a nephrologist, was provided with the initial clinical information. Subsequent data were given in response to his specific questions, with the addition of some supplemental related data. A 71-year-old man was admitted to the Yale–New Haven Hospital with a six-month history of sweats, unexplained fever, weight loss of 9 kg (20 lb), and anemia. A . . .

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