THE EFFECT OF INDOMETHACIN ON PLASMA LEVELS OF PROSTAGLANDIN F2α IN WOMEN IN LABOUR
- 1 May 1977
- journal article
- Published by Wiley in BJOG: An International Journal of Obstetrics and Gynaecology
- Vol. 84 (5) , 339-343
- https://doi.org/10.1111/j.1471-0528.1977.tb12595.x
Abstract
Prostaglandin F2alpha was measured by means of radiommunoassay in the serum of women in the active phase of term labour before and after rectal indomethacin administration. Samples of blood were collected every 20 or 30 seconds, between and during contractions. There was a significant decrease of the level of PGF2alpha in plasma 30 to 30 minutes after indomethacin administration, but the pattern of rapid short-term fluctuations in prostaglandin levels was unaltered.Keywords
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