Bacterial strategies to overcome insect defences
Top Cited Papers
- 10 March 2008
- journal article
- review article
- Published by Springer Nature in Nature Reviews Microbiology
- Vol. 6 (4) , 302-313
- https://doi.org/10.1038/nrmicro1870
Abstract
Recent genetic and molecular analyses have revealed how several strategies enable bacteria to persist and overcome insect immune defences. Genetic and genomic tools that can be used with Drosophila melanogaster have enabled the characterization of the pathways that are used by insects to detect bacterial invaders and combat infection. Conservation of bacterial virulence factors and insect immune repertoires indicates that there are common strategies of host invasion and pathogen eradication. Long-term interactions of bacteria with insects might ensure efficient dissemination of pathogens to other hosts, including humans.Keywords
This publication has 120 references indexed in Scilit:
- Innate Immune Homeostasis by the Homeobox Gene Caudal and Commensal-Gut Mutualism in DrosophilaScience, 2008
- Drosophila Calcineurin Promotes Induction of Innate Immune ResponsesCurrent Biology, 2007
- Insecticidal toxins from Photorhabdus bacteria and their potential use in agricultureToxicon, 2007
- An antibiotic produced by an insect-pathogenic bacterium suppresses host defenses through phenoloxidase inhibitionProceedings of the National Academy of Sciences, 2007
- Mode of action of Bacillus thuringiensis Cry and Cyt toxins and their potential for insect controlPublished by Elsevier ,2006
- Immune pathways and defence mechanisms in honey bees Apis melliferaInsect Molecular Biology, 2006
- Midgut bacteria required for Bacillus thuringiensis insecticidal activityProceedings of the National Academy of Sciences, 2006
- An essential complementary role of NF-κB pathway to microbicidal oxidants in Drosophila gut immunityThe EMBO Journal, 2006
- Transmission ofYersinia pestisfrom an Infectious Biofilm in the Flea VectorThe Journal of Infectious Diseases, 2004
- CloningSerratia entomophilaAntifeeding Genes—a Putative Defective Prophage Active against the Grass GrubCostelytra zealandicaJournal of Bacteriology, 2004