The growth of tendon after denervation or excision of its muscle
- 13 April 1965
- journal article
- research article
- Published by The Royal Society in Proceedings of the Royal Society of London. B. Biological Sciences
- Vol. 162 (987) , 203-209
- https://doi.org/10.1098/rspb.1965.0034
Abstract
The weight and girth of a muscle belly denervated in the three-week-old rabbit eventually grows to about 30%, its total collagen content to almost 300% and the thickness of its tendon to approximately 75% of those of the controls. There is, as occurs during normal growth, the same increase from 0$\cdot $7 to 1$\cdot $25 in the ratio of the thickness of the tendon of peroneus brevis to that of tibialis anterior. If a muscle is completely excised at three weeks, its tendon, which is subjected only to passive tensions during movement, grows to as much as 85% of the girth of its control. If, however, such passive tensions are eliminated as far as is possible, the isolated tendon may grow no more in thickness.Keywords
This publication has 6 references indexed in Scilit:
- The thickness and collagen content of tendon relative to the cross-sectional area of muscle during growthProceedings of the Royal Society of London. B. Biological Sciences, 1965
- The thickness and collagen content of tendon relative to the strength and cross-sectional area of muscleProceedings of the Royal Society of London. B. Biological Sciences, 1965
- The effect of limitation of movement on longitudinal muscle growthProceedings of the Royal Society of London. B. Biological Sciences, 1959
- The collagen and elastin content of the arterial wall in the dogProceedings of the Royal Society of London. B. Biological Sciences, 1957
- Observations on the atrophy of denervated muscleThe Journal of Physiology, 1918