Double diastereocontrol in the synthesis of enantiomerically pure polyoxamic acid
- 1 January 1998
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 23,p. 2641-2642
- https://doi.org/10.1039/a807471b
Abstract
Polyoxamic acid 4 is prepared by a short and efficient process involving diastereochemically matched cycloaddition of 5-(S)-phenylmorpholin-2-one 1 with (S)-glyceraldehyde acetonide 2, followed by sequential hydrolysis and hydrogenolysis of the adduct.Keywords
This publication has 0 references indexed in Scilit: