Plasma polychlorinated biphenyl levels in Dutch preschool children either breast-fed or formula-fed during infancy.
- 1 October 1997
- journal article
- clinical trial
- Published by American Public Health Association in American Journal of Public Health
- Vol. 87 (10) , 1711-1714
- https://doi.org/10.2105/ajph.87.10.1711
Abstract
OBJECTIVES: This study examined the influence of lactational and in utero exposure to polychlorinated biphenyls (PCBs) on plasma PCB levels in children. METHODS: Plasma PCB levels were measured in 173 children at 3.5 years, of whom 91 were breast-fed and 82 were formula-fed in infancy. RESULTS: Median plasma PCB levels were 3.6 times higher in breast-fed children (0.75 microgram/L) than in their formula-fed peers (0.21 microgram/L). Breast-feeding period and breast-milk PCB levels were important predictors for PCB levels in the breast-fed group. For children in the formula-fed group, PCB levels were significantly related to their material plasma PCB levels. CONCLUSIONS: PCB levels in Dutch preschool children are related to transfer of maternal PCBs; therefore, strategies should be aimed at reducing maternal PCB body burden.Keywords
This publication has 19 references indexed in Scilit:
- Perinatal exposure to polychlorinated biphenyls and dioxins and its effect on neonatal neurological developmentEarly Human Development, 1995
- Determinants of Polychlorinated Biphenyls (PCBs) in the Sera of Mothers and Children from Michigan Farms with PCB-Contaminated SilosArchives of environmental health, 1994
- Blood serum levels of PCDFs and PCBs in Yu-Cheng children peri-natally exposed to a toxic rice oilChemosphere, 1994
- PCB and dioxin levels in plasma and human milk of 418 dutch women and their infants. Predictive value of PCB congener levels in maternal plasma for fetal and infant's exposure to PCBs and dioxinsChemosphere, 1994
- Toxic equivalency factors for dioxin-like PCBsChemosphere, 1994
- Polychlorinated Biphenyls (PCBs): Environmental Impact, Biochemical and Toxic Responses, and Implications for Risk AssessmentCritical Reviews in Toxicology, 1994
- Intake of 2,3,7,8 chlorine substituted dioxins, furans, and planar PCBs from food in the Netherlands: Median and distributionChemosphere, 1993
- Determinants of polychlorinated biphenyls (PCBs), polybrominated biphenyls (PBBs), and dichlorodiphenyl trichloroethane (DDT) levels in the sera of young children.American Journal of Public Health, 1989
- Rate of decrease and half-life of polychlorinated biphenyls (PCBs) in the blood of mothers and their children occupationally exposed to PCBsArchives of Environmental Contamination and Toxicology, 1984
- Revised standards for triceps and subscapular skinfolds in British children.Archives of Disease in Childhood, 1975