RELEASE OF CHOLECYSTOKININ IN RESPONSE TO FOOD AND INTRADUODENAL FAT IN PIGS, DOGS AND MAN

  • 1 January 1984
    • journal article
    • research article
    • Vol. 159  (6) , 557-561
Abstract
Endogenous cholecystokinin-33 release in response to physiologic stimuli (meal, fat) were compared in pigs, dogs and man. Plasma levels of cholecystokinin-33 were monitored using a radioimmunoassay for cholecystokinin which detects only cholecystokinin-33 and cholecystokinin-39. Ingestion of a meal caused release of cholecystokinin-33 within 5, 20 and 120 min in man, pigs and dogs, respectively. Intraduodenal administration of corn oil resulted in a significant release of cholecystokinin-33 within 20 min in dogs, pigs and man.

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