Detection of the HB Quong SZE Mutation in a Chinese Family by Selective Amplification of the α2-Globin Gene and Restriction Map Analysis with MSP I
- 1 January 1991
- journal article
- case report
- Published by Taylor & Francis in Hemoglobin
- Vol. 15 (6) , 535-540
- https://doi.org/10.3109/03630269109027901
Abstract
The polymerase chain reaction technique combined with restriction map analysis with Msp I and hybridization with synthetic oligonucleotide probes has been used to identify Hb Quong Sze [alpha 125(H8)Leu----Pro] in a Chinese family in Guangxi (Quong Sze), P. R. China. Our data and those described in an earlier publication (1) indicate that the Hb Quong Sze carriers originate from the same province of the People's Republic of China, namely Guangxi.Keywords
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