EFFECTS OF NEONATAL EXPOSURE TO PAINT THINNER ON THE DEVELOPMENT OF SWIMMING IN RATS

  • 1 January 1980
    • journal article
    • research article
    • Vol. 2  (1) , 1-5
Abstract
Rats were exposed to paint thinner 2 times a day for 10 min on days 1-30 of postnatal life. Effects on physical development, swimming ability and escape latency from water were evaluated. Maturation of swimming behavior and general physical development were delayed about 2-4 days in experimental animals compared with non-exposed littermate controls. Exposure to this organic solvent during early postnatal period interfered with development of cortico-subcortical neural structures underlying swimming and locomotion.