ISOLATED ADRENOCORTICOTROPHIN DEFICIENCY AND EMPTY SELLA ASSOCIATED WITH HYPOTHYROIDISM

Abstract
A case of isolated ACTH deficiency is described. The patient had an empty sella and longstanding radioiodine induced hypothyroidism. The association between isolated ACTH deficiency, empty sella and hypothyroidism is reviewed. It has not been previously recognized that the commonest endocrine association of isolated ACTH deficiency is primary thyroid failure. ACTH secretion does not recover following thyroxine replacement treatment.