THE STRUCTURAL CHANGES WHICH TAKE PLACE IN THE THYROID GLANDS OF GUINEA PIGS DURING THE PROCESS OF COMPENSATORY HYPERTROPHY UNDER THE INFLUENCE OF IODINE ADMINISTRATION
- 1 January 1929
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 13 (1) , 49-62
- https://doi.org/10.1210/endo-13-1-49
Abstract
Administration of KI in the guinea pig, during the process of compensatory hypertrophy of the thyroid and in the normal guinea pig, causes a stimulation of the gland tissue, in which softening and solution and increased growth processes are noticeable. In the normal gland the growth processes initiated by I are prominent, whereas in compensatory hypertrophy, where removal of a great part of the gland tissue as such causes marked stimulation, changes in the colloid are more pronounced. Structural changes thus produced make it possible in many cases to recognize whether I has been administered during the process of compensatory hypertrophy. The various changes induced by the administration are discussed and the possible relationship which these changes have to each other.This publication has 2 references indexed in Scilit:
- The effect of the oral administration of potassium iodide and thyroid substance on the mitotic proliferation and structure of acini in the thyroid gland in guinea pigs1928
- Studies on compensatory hypertrophy of the thyroid gland VII. Further investigation of the influence of iodin on hypertrophy of the thyroid gland with an interpretation of the differences in the effects of iodin on the thyroid gland under various pathologic conditions1926