Evaluation of Reconstruction Windows for Multislice Computed Tomography in Quantification of Coronary Calcium

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Abstract
Gerber TC, O’Brien PC, Pastor K, et al. Evaluation of reconstruction windows for multislice computed tomography in quantification of coronary calcium. Invest Radiol 2003;38:108–118. Rationale and Objectives. To search for an optimum reconstruction window in retrospectively gated multislice computed tomography (MSCT) for quantification of coronary calcium. Materials and Methods. Coronary calcium quantified was examined as Agatston and volume scores by two experienced observers at 10 time points across the R-R interval of the electrocardiogram in 42 patients. A combination of statistical approaches was used to evaluate the distributions of minimum and maximum scores and of interobserver variability for both scoring methods across the cardiac cycle. Results. Based on the combination of evaluation approaches, 60% to 70% of the R-R interval appeared to be the optimum time point for obtaining maximum calcium scores with minimum interobserver variability. The optimum time point was more clearly defined for the Agatston score than for the volume score. Conclusion. A reconstruction window beginning at 60% to 70% of the R-R interval seems to be most advantageous for retrospective gating of MSCT studies performed to quantify coronary calcium.