A methodological study of arterial wall function using ultrasound technique

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Abstract
We aimed to establish reference values for three important properties of the arterial wall using a conventional ultrasound scanner. We measured: (1) intima–media thickness (IMT) of the carotid arteries with the internal trace function of the ultrasound system; (2) wall stiffness by pulsatile diameter changes in the right common carotid artery assessed by M‐mode; and (3) endothelial function expressed as flow‐mediated dilatation (FMD) of the brachial artery. IMT and wall stiffness measurements and reproducibility were compared with those obtained by external analysing systems. All variables were obtained in healthy subjects (n = 20), 29–53 years old. IMT increased with age (PPPP<0·01), smaller FMD in men. We conclude that it is possible to characterize arterial wall function non‐invasively in an adequately reproducible manner using a conventional ultrasound system in healthy middle‐aged men and women.

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