Biocatalytic preparation of chiral alcohols by enantioselective reduction with immobilized cells of carrot
- 1 January 1995
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 10,p. 1295-1298
- https://doi.org/10.1039/p19950001295
Abstract
The ability of immobilized cells of Daucus carota to reduce enantioselectively organic foreign substrates has been examined. The immobilized plant cells reduced, with excellent enantioselectivity, prochiral ketone substrates such as keto esters, aromatic ketones and heterocyclic aromatic ketones, leading to the corresponding chiral secondary alcohols with an enantiomeric purity of 52–99% ee in a chemical yield of 30–63%.Keywords
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